/*Version 1.0, 2019-11-13 */



/* biogen-blue: #2573BA */
/* biogen-green: #6DAD46 */
/* biogen-darkblue: #6FA287 */
/* bioegen-lightblue: #B1CBEB */
/* background: #fff */

:root {
    --main-bg-color: white;
    --padding: 1.25rem;
    --biogen-blue: #2573BA;
    --biogen-dark-blue: #005B7F;
    --nn-link: #009fda;
    --nn-black: #000;
    --nn-nav-active: #82786f;
    --nn-text: #333333;
    --nn-alert: #e64a0e;
    --flyout-bg-biogen: #f1f1f1;
    --flyout-item-divider: #b3cbe0;
    --dev-spot-bg: #efefef;

    /* text sizes */
    --paragraph-sized: 1rem;
    --h1: 3rem;
    --h2: 1.5rem;
    --h3: 1.728rem;
}

/* removed items */
.main-nav .wrapper > ul > li > a::after, .main-nav .caret, .main-nav .caret::before, .template--home .page-title .page-utils, .page-header-generic, .main-nav .on .caret, .safety_info, .template_generic .breadcrumb, .template--generic-one-column .breadcrumb, footer .back-to-top, .wrapper-full-width .full-width > div:nth-child(2) .cardContainer-content::before, .main-nav .wrapper > ul > li.over .caret, #footer .row .col:first-child h2, header .main-nav .wrapper ul > li:hover ul li:hover:after, .logo-options .col1 .last, .carousel-container .slickCarousel .slick-prev, .carousel-container, .jwplayer .jwdisplayIcon .jwtext, .slickCarousel .slick-next {
    display: none !important;
}

/* various overwrite rules */
.frontpage-wrapper {
    margin-top: 20px !important;
    width: 1145px;
    max-width: 100%;
    overflow: hidden;
    margin: 0 auto;
}

.space-wrapper {
    height: 20vh;
}

.main.generic-page.full-width {
    max-width: 1145px;
    margin: 0 auto;
    width: 100%;
}

.ipadright {
    padding: 0 !important;
}

.modal-buttons a {
    padding: 0.875rem 1.5rem;
}

p.first img {
    height: 75px !important;
    width: auto;
}

@media all and (min-width: 376px) {
    p.first img {
        height: 75px !important;
        width: auto;
    }
}

@media all and (min-width: 768px) {
    p.first img {
        height: unset !important;
        width: auto;
    }
}

/*Accordion setup*/
.accordion {
    margin: 0;
    padding: 0;
    border: 0;
    width: auto;
}


@media all and (min-width: 376px) {
}

.accordion .accordionElementHeader h4 {
    margin: 0;
    padding: 0;
    font-size: inherit;
    text-transform: none;
    font-family: inherit;
    font-weight: 700;
    line-height: 1;
}


.accordion .columncontrol .row {
    background: #fff;
    width: 100%;
    margin: 0 auto;
}


.modal-content {
    padding-top: 0 !important;
}

.negative-margin {
    margin-bottom: 40px !important;
}

.negative-margin > div > div:first-child {
    margin-bottom: -24px !important;
}


/* ...this one normally used for introducing the page */

.wrapper {
    padding: 0;
}

.col-xs-1, .col-sm-1, .col-md-1, .col-lg-1, .col-xs-2, .col-sm-2, .col-md-2, .col-lg-2, .col-xs-3, .col-sm-3, .col-md-3, .col-lg-3, .col-xs-4, .col-sm-4, .col-md-4, .col-lg-4, .col-xs-5, .col-sm-5, .col-md-5, .col-lg-5, .col-xs-6, .col-sm-6, .col-md-6, .col-lg-6, .col-xs-7, .col-sm-7, .col-md-7, .col-lg-7, .col-xs-8, .col-sm-8, .col-md-8, .col-lg-8, .col-xs-9, .col-sm-9, .col-md-9, .col-lg-9, .col-xs-10, .col-sm-10, .col-md-10, .col-lg-10, .col-xs-11, .col-sm-11, .col-md-11, .col-lg-11, .col-xs-12, .col-sm-12, .col-md-12, .col-lg-12 {
    padding: 0;
}

.utility-nav .navbar-nav > li > a, .utility-nav .navbar-text {
    padding: 0.25rem;
    width: 130px;
    text-align: center;
    height: 50px;
    line-height: 25px;
    display: block;
    float: right;
}

.highlighterPlug {
    color: #2573BA;
    font-weight: 400;
    text-transform: none;
    font-size: 1.5rem;
    font-style: italic;
}

.utility-nav .wrapper, .logo-options .wrapper, .main-nav .wrapper, .content .wrapper, .isi .wrapper, .references .wrapper, footer .wrapper {
    max-width: 1145px;
    padding: 0;
}

.no-touchcapable .main-nav .wrapper > ul > li > a:hover, .touchcapable header .main-nav .wrapper > ul > li > .on, header .main-nav .wrapper > ul > .over > a {
    background: none !important;
    border-bottom: 0;
    font-family: inherit;
}

@media all and (min-width: 1023px) {

    .utility-nav .navbar-nav > li > a, .utility-nav .navbar-text {
        padding: 0;
        background: none;
        width: auto;
        height: 50px;
        line-height: 25px;
        display: flex;
        flex-flow: row;
    }


    .no-touchcapable .main-nav .wrapper > ul > li > a:hover, .touchcapable header .main-nav .wrapper > ul > li > .on, header .main-nav .wrapper > ul > .over > a {
        border-bottom: 7px solid #2573BA !important;
    }
}

.column-control-column {
    padding: 0;
}

/*HEADER region defintions*/
header {
    background: #fff;
    height: 75px;
    position: relative;
}

header .main-nav .wrapper ul > li a.on ul {
    display: block;
}

header::before {
    background: #6DAD46;
    content: "";
    width: 100%;
    height: 17px;
    display: none;
}

header .utility-nav {
    background: #fff;
    box-shadow: none;
    margin: 0;
    font-size: inherit;
    font-family: inherit;
    text-shadow: unset;
    display: block;

    position: absolute;

    right: 0;
}

header .navbar-right {
    background: none;
    width: unset !important;
    float: right !important;
}

header .navbar-nav {
    margin-top: 5px;
    position: relative;
    right: 9px;
    float: right !important;
}

header .navbar-right .navbar-link {
    background: #2573BA;
    padding: 0.5rem 1.5rem;
    margin-left: 20px;
    height: 25px;
    line-height: 1;
    width: 115px;
    text-align: left;
}

header .navbar-right p a:nth-child(1) {
    background: none !important;
    color: #333;
    background-size: 15% !important;
}

header .navbar-right p a:nth-child(1) {
    background: none !important;
    text-shadow: none;
    color: #333;
    font-family: 'Libre Franklin', sans-serif !important;
    text-decoration: underline;
    font-size: 0.75rem;
    font-weight: 400;
    text-decoration: none;
}

header .navbar-right p a:nth-child(1):hover {
    color: #333;
}

header .main-nav .wrapper ul > li > a {
    color: #2573BA !important;
    font-family: inherit !important;
    text-align: left;
    font-size: 0.875rem;
    font-weight: 400;
    transition: none !important;
    line-height: 56px;
    height: 56px;
    margin-top: unset;
    display: block;
    padding: 0 1.5rem;
    text-transform: none;
}

header .main-nav .wrapper .level-1::after {
    content: "";
    display: block;
    position: absolute;
    right: 0;
    width: 1px;
    background: #e8eff8;
    height: 40px;
    top: 7px;
}

header .main-nav .wrapper ul > li ul .level-2 {
    text-align: left;
    padding: 0;
    border-bottom: 1px solid var(--flyout-item-divider) !important;
    background: #fff !important;
}

header .main-nav .wrapper ul > li ul .level-2 a {
    display: block;
    line-height: unset;
    opacity: 1 !important;
    padding: 1.25rem 2rem 1.25rem 3rem !important;
}

header .main-nav .wrapper ul > li {
    background: #fff;
    height: 56px;
    position: relative;
}

header .main-nav .wrapper ul > li:hover {
    background: #f3f3f3;
}

header .main-nav .wrapper ul > li:hover a {
    color: #2573BA !important;
}

header .main-nav .wrapper ul > li:hover ul li a {
    color: #2573BA !important;
    border: none;
    height: auto;
}

header .main-nav .wrapper ul > li:hover ul li:hover a {
    border: none;
    color: #fff !important;
    opacity: 1 !important;
    background: #2573BA !important;
}

header .main-nav .wrapper ul li + li a {
    border-left: none;
}

header .main-nav .wrapper ul > li ul li {
    background: none !important;
    display: block;
}

header .main-nav .wrapper ul > li ul li:hover {
    color: #2573BA !important;
    display: block;
}

header .main-nav .wrapper ul > li.over ul {
    display: block !important;
    background: var(--flyout-bg-biogen);
    padding: 15px 0 0;
    top: 55px !important;
    width: 35em;
}

header.sticky.stickytoTop {
    top: -118px !important;
}

header .main-nav .wrapper ul > li {
    height: auto;
    border-bottom: 1px solid #e2e2e2;
    background: #f3f3f3;
}

@media screen and (min-width: 1024px) {
    header {
        height: 185px;
        position: relative;
        display: flex;
    }

    header .fixed-offset {
        padding: 0 !important;
        position: absolute;
        height: auto;
        top: 17px;
        max-width: 1145px;
        width: 100%;
        left: 0;
        right: 0;
        margin-left: auto;
        margin-right: auto;
    }

    header .fixed-offset[style] {
        padding: 0 !important;
    }

    header::before {
        background: #6DAD46;
        content: "";
        width: 100%;
        height: 17px;
        display: block;
    }

    header .main-nav .wrapper ul > li {
        background: transparent;
        height: 56px;
        position: relative;
    }

    header .main-nav .wrapper ul > li:hover {
        background: #fff !important;
    }

    header .main-nav .wrapper ul > li {
        height: 56px;
        border-bottom: 0;
        background: none;
    }

    header .main-nav .wrapper ul > li ul {
        display: none !important;
    }

    header .main-nav .wrapper ul > li:hover {
        background: transparent !important;
    }

    header .main-nav .wrapper ul > li:hover a {
        color: #2573BA !important;
    }

    header .main-nav .wrapper ul > li > a {
        color: red;
    }

    header .navbar-right .navbar-link {
        background: #2573BA;
        padding: 1.2rem 1.5rem;
        margin-left: 20px;
        height: 50px;
        line-height: 1;
        width: auto;
    }

    header .main-nav .wrapper ul > li ul .level-2 a {
        padding: 1.25rem 1.875rem !important;
    }

}


/*NAVIGATION region defintions*/
.main-nav {
    background: #fff;
    border: 0.2px solid #D1D3D3;
    -webkit-font-smoothing: antialiased;
    -moz-font-smoothing: antialiased;
    -o-font-smoothing: antialiased;
    -moz-osx-font-smoothing: grayscale;
    text-align: center;
    height: 56px;
    box-shadow: none !important;
}

.main-nav ul ul {
    display: none;
    background: #f1f1f1;
    padding: 0;
}

.main-nav::after {
    content: "";
    height: 8px;
    width: 100%;
    box-shadow: 0 3px 4px 0 #CDCDCD;
    display: block;
    position: relative;
    bottom: 10px;
    z-index: 5;
}

.main-nav .wrapper > ul ul li {
    border-bottom: none;
    margin: 0;
    height: 65px !important;
    line-height: 25px;
}

.main-nav .wrapper > ul > li > ul > li > a {
    color: #2573BA !important;
}

.main-nav .wrapper > ul > li > ul > li.over > a, .main-nav .wrapper > ul > li > ul > li.over > a:hover {
    background: transparent;
    opacity: 0;
    font-weight: 100 !important;
}

.main-nav .wrapper > ul ul > li + li {
    margin-left: 0;
}

.main-nav .wrapper > ul > li > a.on {
    background: none;
}

.main-nav .wrapper > ul > li > a::before {
    display: none;
}

.main-nav .wrapper > ul > li.has-children > a::before {
    color: #5c6770;
    content: "+";
    font-style: normal;
    font-weight: 400;
    -webkit-font-smoothing: antialiased;
    -moz-osx-font-smoothing: grayscale;
    -webkit-transition: color, 0.1s, linear;
    -moz-transition: color, 0.1s, linear;
    transition: color, 0.1s, linear;
    font-size: 1.3rem;
    font-family: inherit;
    z-index: 2;
    display: block;
}

.main-nav .wrapper > ul > li.has-children > a.on::before {
    content: "-";
    font-size: 1.5rem;
    padding: 0 0 0 7px;
    right: 23px;
    top: 27px;
}


.sidebar-offcanvas {
    position: absolute;
    top: 0;
    width: 80%;
}

.row-offcanvas-left .sidebar-offcanvas {
    left: -80%;
}

@media all and (min-width: 516px) {
    .sidebar-offcanvas {
        width: 60%;
    }

    .row-offcanvas-left .sidebar-offcanvas {
        left: -60%;
    }
}

@media all and (min-width: 1023px) {
    .sidebar-offcanvas {
        top: inherit;
        width: 100%;
        position: absolute;
        bottom: 0;
        z-index: 100;
    }

    .row-offcanvas-left .sidebar-offcanvas {
        left: 0;
    }
}

@media all and (min-width: 1024px) {
    .main-nav .wrapper > ul > li.has-children > a::before {
        display: none;
    }
}

/*NAVIGATION region defintions - logo placement*/
.logo-options {
    background: #fff;
    height: 165px;
}

.logo-options .row {
    margin: 0;
}

.logo-options .col1 .first {
    margin: 0 auto -34px;
    padding: 0;
    width: auto;
    display: inline-block;
    position: relative;
    left: 40%;
    right: 0;
}

.logo-options .col1 .first a {
    max-width: 166px;
    margin: 0;
    width: 100%;
}

.logo-options .wrapper .row > div:first-child {
    position: relative;
    top: -55px;
}

.logo-options .form-inline {
    position: absolute;
    top: 24px;
    right: 10px;
}

.logo-options .col3 .form-inline {
    position: absolute;
    top: 24px;
}

.logo-options .col3 form input {
    width: 100%;
    height: 54px;
    line-height: 54px;
    padding-top: 0;
    padding-bottom: 0;
    padding-left: 25px;
    border-radius: 0;
    font-size: inherit;
    border: none;
    background: #f6f6f6;
    margin-right: 29px;
    position: relative;
    left: -30px;
}

.logo-options .col3 form button {
    position: absolute;
    bottom: -1px;
    right: -10px;
    height: 55px;
    padding: 0;
    font-size: inherit;
    border-radius: 0;
    background: url(/content/dam/commercial-eu/neurology/portal/microsites/images/plegridy/icon-search.png) no-repeat center center #6DAD46 !important;
    background-size: 35% !important;
    border: none;
    width: 80px;
}

.logo-options .col3 form button {
}

/*NAVIGATION region defintions - flyout logic*/
.level-1.has-children.over {
    border-bottom: none;
}

.level-1.has-children.over::before {
    content: "";
    display: block;
    position: absolute;
    top: 54px;
    left: 40%;
    width: 20px;
    height: 30px !important;
    border-bottom: none;
    border-top: solid 15px #2573BA;
    border-left: solid 10px transparent;
    border-right: solid 10px transparent;
    z-index: 5000;
}

.level-1.here::before {
    display: none;
}

.level-1.here {
    background: #f3f3f3 !important;
}

@media all and (min-width: 1024px) {
    .level-1.has-children.over {
        border-bottom: 7px solid #2573BA;
    }

    .logo-options .col1 .first {
        left: 0;
        right: 0;
    }

    .logo-options .wrapper .row > div:first-child {
        position: relative;
        top: -55px;
        left: unset;
    }

    .level-1.here::before {
        content: "";
        display: block;
        position: absolute;
        top: 44px;
        left: 0;
        width: 100%;
        height: 10px !important;
        border-bottom: solid 5px #2573BA;
        border-left: none;
        border-right: none;
        border-top: none;
        z-index: 5000;
    }

    .level-1.here {
        background: none !important;
    }
}


/*CONTENT region defintions*/
.content {
    clear: left;
    padding-top: 50px;
}

.content .close span {
    display: block;
    margin: 0;
    width: 2rem;
    height: 2rem;
    background-color: #69B3E7;
    color: #fff;
    border-radius: 0;
    line-height: 2rem;
    font-size: 2rem;
    font-weight: 400;
}

.content p {
    line-height: 1.5;
    font-size: 1rem;
    font-family: inherit;
    color: unset;
    margin-bottom: 10px;
    font-weight: 300
}

.content ul {
    font-weight: 400;
    font-size: 1rem;
}

.content .thumbnail-list {
    background: #fff;
    clear: left;
    display: flex;
    flex-flow: row;
    flex-wrap: wrap;
    margin: 0;
}

.content .thumbnail-block {
    background: #2573BA;
    flex: 1 1 30% !important;
    width: unset !important;
    margin: 0 30px 30px 0;
}

.content .thumbnail-block .thumbnail {
    width: unset;
    padding: 0;
    margin: 0;
}

.content .thumbnail-block .thumbnail img {
    display: block;
    width: unset;
    margin: 0;
    padding: 0;
}

.content .thumbnail-block .thumbnail + p {
}

/*CONTENT region - titles*/
body .content h1 {
    font-size: 1.75rem;
    font-family: inherit;
    line-height: 1.2;
    padding: 0;
    margin: 0 0 1.875rem;
    width: 90%;
}

body .content h2 {
    font-size: 1.75rem;
    color: var(--biogen-dark-blue);
    font-family: inherit;
    line-height: 1.3;
    font-weight: 400;
    margin: 0 0 1rem;
    width: 90%;
}

body .content h2.modal-title {
    width: 100%;
}

body .content .column-control-column h1, body .content .column-control-column h2 {
    font-size: 1.5rem;
    margin: 0.5rem 2.5rem 1.875rem;
    line-height: 1.2;
}

body .content .signin-register .column-control-column h1, body .content .signin-register .column-control-column h2 {
    font-size: 2.25rem;
    margin: 0 2.5rem 1.875rem 0;
    line-height: 2.5rem;
}

body .content .cardContainer-content h1, body .content .cardContainer-content h2 {
    font-size: 1.75rem;
    line-height: 2rem;
    margin: 0 0 0.65rem;
    color: #fff;
    width: inherit;
}


body .content .spots .column-control-column h2 {
    font-weight: 500;
    text-align: left;
    margin: 3.5rem 3.5rem 1rem;
    display: inline-block;
    width: 100%;
    font-size: 2.25rem !important;
}

body .content .wrapper-full-width .spots .column-control-column p {
    text-align: left;
    margin: 0.5rem 3.5rem;
    font-size: 1.2rem;
}

body .content .spots .column-control-column .affiliatebutton a {
    padding: 0;
    border: 0 !important;
    text-transform: none;
    font-size: 1.3rem;
    font-weight: 500;
}


@media all and (min-width: 768px) {
    body .content h1 {
        font-size: 3rem;
        line-height: 3.625rem;
        padding: 0;
        margin: 0 0 1.875rem;
        width: 90%;
    }

    body .content h2 {
        font-size: 2.25rem;
        line-height: 2.5rem;
        margin: 0 0 1.875rem;
        width: 90%;
    }

    body .content .column-control-column h1, body .content .column-control-column h2 {
        font-size: 2.25rem;
        margin: 2.5rem 2.5rem 1.875rem;
        line-height: 2.5rem;
    }

    body .content .cardContainer-content h1, body .content .cardContainer-content h2 {
        font-size: 2.25rem;
        margin: 0 0 2.25rem;
        line-height: 2.75rem;
    }
}

@media all and (min-width: 1024px) {
    body .content h1 {
        font-size: 3rem;
        line-height: 3.625rem;
        padding: 0;
        margin: 0 0 1.875rem;
        width: 90%;
    }

    body .content h2 {
        font-size: 2.25rem;
        line-height: 2.5rem;
        margin: 0 0 1.875rem;
        width: 90%;
    }

    body .content .cardContainer-content h1, body .content .cardContainer-content h2 {
        font-size: 2.25rem;
        margin: 0 0 2.25rem;
        line-height: 2.75rem;
    }
}

/*CONTENT region - body text*/
body .content .column-control-column p {
    margin: 0 1rem;
}

body .content .signin-register .column-control-column p {
    margin: 0 2.5rem 0 0;
}

body .content .cardContainer-content p {
    margin: 0;
    color: #fff;
}

body .content .column-control-column .mediatile.section .video-mediatile, body .content .column-control-column .embed-container {
    margin: 2.5rem;
}

body .content .media-heading {
    margin: 0 2.5rem 1.875rem;
}

body .content .media-body p {
    margin: 0 2.5rem;
}

body .content .blue .column-control-column p {
    color: #fff;
    text-align: center;
}

@media all and (min-width: 376px) {
    body .content .cardContainer-content p {
        margin: 0;
    }
}

/*CONTENT region - images and text*/
.media {
    background: #808080;
    position: relative;
    display: flex;
    height: 500px;
    padding: 0;
    margin-top: 0;
}

.content .main .main-teasertile .media .media-body {
    text-align: right;
    padding-top: 150px;
    width: 100% !important;
}

.content .main .main-teasertile .media .media-body p {
    font-size: 1.4rem;
}

.content .main .main-teasertile .media .media-body p a {
    display: block;
    background: rgba(255, 255, 255, 0.25);
    float: right;
    /*padding: 5px 30px;*/
    margin-top: 25px;
    color: #ffffff;
    text-decoration: none;
    font-size: 1.3rem;
    font-weight: 500;
}

.media img {
    position: absolute;
    left: 0;
    top: 0;
    width: 100%;
    max-width: 100%;
    height: 500px !important;
    object-fit: cover;
}

.media .media-heading {
    color: #fff;
    font-size: 1.25rem;
}

.media p {
    color: #fff;
}

.media > a {
    width: 100%;
    position: absolute;
    order: 2;
    margin: 0;
    padding: 0;
    height: 100%;
}

.media .hidden-xs {
    display: block !important;
}

.media > .media-body {
    width: 100%;
    position: relative;
    order: 1;
    background: linear-gradient(to top, #2573BA, transparent);
    padding-top: 2.5rem;
    top: 30%;
}

.without-blue-header .media > .media-body {
    background: transparent;
}

@media only screen and (min-width: 768px) {
    .media {
        height: 380px;
    }

    .media .media-heading {
        color: #fff;
        font-size: 2.5rem;
    }

    .media > .media-body {
        width: 50%;
        top: 0;
        background: -webkit-linear-gradient(right, #2573BA, transparent);
        background: -o-linear-gradient(right, #2573BA, transparent);
        background: linear-gradient(to right, #2573BA, transparent);
    }

    .without-blue-header .media > .media-body {
        background: transparent;
    }

    .media img {
        width: 100%;
        max-width: 100%;
    }

    .dark-gradient .media > .media-body {
        background: -webkit-linear-gradient(right, #444, transparent);
        background: -o-linear-gradient(right, #444, transparent);
        background: linear-gradient(to right, #444, transparent);
    }

    .black-gradient .media > .media-body {
        background: -webkit-linear-gradient(right, #2f2f2f, transparent);
        background: -o-linear-gradient(right, #2f2f2f, transparent);
        background: linear-gradient(to right, #2f2f2f, transparent);
    }
}


/*FOOTER region defintions*/
footer {
    background: #fff;
    font-size: inherit;
    display: flex;
    max-width: 1145px;
    width: 100%;
    margin: 0 auto;
}

#footer .row {
    width: 1145px;
    padding: 2.5rem 0;
}

#footer .row .col:first-child {
    width: 70%;
}

#footer .row .col:first-child ul {
    margin: 0;
    padding: 0 2.5rem;
}

#footer .row .col:first-child ul li {
    margin: 0;
    padding: 0 1.5rem;
    display: inline-block;
}

#footer .row .col:first-child ul li a {
    color: #2573BA !important
}

#footer .row .col:last-child {
    width: 30%;
    padding: 0 70px;
}

html {
    font-size: 16px;
}

body {
    background: #fff;
    font-family: "Helvetica Neue", Helvetica, Arial, sans-serif !important;
    font-weight: 400;
}

/* content area */

.form-control:focus {
    border-color: #66afe9;
    outline: 0;
    transition: none !important;
}

.main-nav-list {
    height: unset;
    list-style-type: none;
    margin: 0 !important;
    padding: 0;
    white-space: nowrap;
    text-align: left;
    width: 100% !important;
    position: relative !important;
}


.col-md-6 .media > .media-body {
    width: 100%;
    position: relative;
    order: 1;
    padding: 2.5rem;
}


.mediatile.section {
    display: flex;
    flex-flow: column-reverse;
}


.page-header-generic + .content {
    padding: 20px 20px 20px;
    margin: 0 auto 100px;
}

@media only screen and (min-width: 768px) {
    .page-header-generic + .content {
        padding: 15px 20px 20px;
        margin: 0 auto;
    }
}

/* columncontrol */
.columncontrol .row {
    background: #fff;
    width: auto;
    margin: 0 auto;
}

/* text block with solid colored background */
.cardContainer {
    display: inline-block;
    margin-bottom: 0;
    min-height: 350px;
    padding: 1.4rem !important;
    background-position: unset !important;
}

.cardContainer:hover {
    background-size: unset !important;
}

.cardContainer:hover .button a.netherLandsDefaultButton {
    background: #005B7F !important;
}

.cardContainer:hover h4 {
    color: #fff;
    background: #005B7F;
}

.cardcontainer:first-child, .main .cardcontainer:first-child > .cardContainer {
    padding: 0;
    margin-bottom: 10px;
}

.cardcontainer + .cardcontainer {
    margin-top: 2.75rem !important;
}

.cardContainer .cardContainer-content {
    text-align: center;
    padding: 0;
}

.cardContainer .cardContainer-content h1, .cardContainer .cardContainer-content h2 {
    color: #fff;
}

.cardContainer .cardContainer-content h3 {
    color: #fff;
    font-size: 1.75rem;
    margin: 3rem 3rem -4rem;
}

.cardContainer-content h1, .cardContainer-content p {
    color: #fff !important;
    font-family: inherit;
}

.cardContainer-content p {
    font-size: 1rem;
    line-height: 1.5;
    font-weight: 400;
}

.cardContainer-content p:last-child {
    margin-bottom: 2.5rem !important;
}


@media only screen and (min-width: 768px) {
    .cardContainer {
        padding: 2.5rem !important;
    }

    .col-sm-6.col-md-3 .cardContainer {
        padding: 2.5rem 1.25rem !important;
    }
}


/* video embedding */
.embed-container {
    margin-bottom: 50px;
}

/* floating media/text spots */
.spots .columncontrol .row {
    display: flex;
    margin-bottom: 25px;
    flex-flow: column nowrap;
    position: relative;
}

.spots .columncontrol .row .col-sm-4 {
    width: 100%;
    margin: 0 0 20px 0;
}

.spots.blue .columncontrol .row > div {
    background: #2573BA;
    padding-bottom: 5rem;
    min-height: 530px;
}

.spots.blue .columncontrol .row > div:first-child {
    background: #6DAD46;
!important;
}

.spots .column-control-column div.image img {
    display: block;
    padding: 0 !important;
    width: 100%;
}

.spots h1, .spots h2, .spots p {
}

.spots h2 {
}

.spots .col h2, .spots .col h3 {
    color: #fff;
    font-size: 1.125rem !important;
    margin: 1.25rem 2.5rem;
}

.spot {
    display: flex;
    flex-direction: column;
    float: left;
}

.spot.w-33 {
    width: 31%;
    margin: 1%;
}

.spot.w-50 {
    width: 50%;
}

.spot.blue {
    background: #2573BA;
    color: #fff;
}

.spot figcaption {
    padding: 1.25rem 2rem;
}

.spot figcaption h2 {
    color: #fff;
    font-size: 1.125rem;
    font-weight: 700;
}

@media all and (min-width: 516px) {
    .spots .columncontrol .row {
        flex-flow: row wrap;
        left: -0.5rem;
        width: calc(100% + 0.5rem);
    }

    .spots .columncontrol .row .col-sm-4 {
        width: 48.25%;
        margin: 0 0 0 1.75%;
    }
}

@media all and (min-width: 768px) {
    .spots .columncontrol .row {
        left: -1.25rem;
        width: calc(100% + 1.25rem);
    }

    .spots .columncontrol .row .col-sm-4 {
        width: 31.55%;
        margin: 0 0 0 1.75%;
    }
}


/* table styling */
.content table {
    width: 100%;
    margin-bottom: 30px !important;
}

.content table tbody tr:first-child {
    background: #B1CBEB !important;
}

.content table tbody tr:nth-child(odd) {
    background: #E8EFF8 !important;
}

.content table tbody tr:nth-child(odd) {
    background: #fff;
}

.content table tbody tr td {
    padding: 0.9375rem 1.25rem;
}

.content table tbody tr th {
    font-weight: 700;
    padding: 0.9375rem 1.25rem;
}

/* buttons - div-wrapper component have to be used around the button component */
.netherLandsDefaultButton {
    background: transparent;
    border: 1px solid #fff !important;
    text-align: center !important;
    width: 50% !important;
    margin: 0 auto !important;

}

.content a.netherLandsDefaultButton {
    display: inline !important;
    width: 100%;
    background: transparent;
    font-size: inherit;
    font-weight: 400;
    color: unset;
    padding: 4.9375rem 2.5rem;
    margin: unset !important;
    text-align: left;
    text-transform: uppercase;
    text-decoration: none;
    cursor: pointer;
    border: none;
    border-radius: 0;
}

.spots.blue a.netherLandsDefaultButton {
    color: #fff;
}


@media only screen and (min-width: 320px) {
    .content a.netherLandsDefaultButton {
        display: inline !important;
        width: 100%;
        background: transparent;
        font-size: inherit;
        font-weight: 400;
        color: unset;
        padding: 0.9375rem 2.5rem;
        margin: unset !important;
        text-align: left;
        text-transform: uppercase;
        text-decoration: none;
        cursor: pointer;
        border: none;
        border-radius: 0;
    }
}

/* button styling in case HTML component is used to mark up a button */
.button {
    border-radius: 10px;
    display: flex;
    margin: 30px auto 0;
    justify-content: center;
}

.button.left {
    justify-content: left;
}


.button a {
    border-radius: 10px;
    max-width: 250px;
    width: 100%;
}

.button.green a {
    background: #6DAD46;
    color: #fff !important;
    text-decoration: none !important;
}

.button.blue a {
    background: #2573BA;
    color: #fff !important;
    text-decoration: none !important;
}

.button.outline a {
    background: transparent;
    border: 1px solid #2573BA;
    color: #2573BA;
}

.button.solid a {
    border: none;
    border-radius: 5px;
}

.button.transparent {
    background: transparent;
    border: none;
    color: #2573BA;
}

.spots .button.outline {
    position: absolute;
    bottom: -20px;
    right: 0;
    left: 0;
    justify-content: flex-start;
    margin: 3.5rem;
}

.spots .button.outline a {
    background: transparent;
    border: 1px solid #2573BA;
    color: #fff;
}

.spots.blue .button.outline a {
    color: #fff !important;
    text-decoration: none !important;
}

/* image/video slider */
.carousel-videoscroll .inner-media {
    visibility: visible !important;
}

.carousel-container .slickCarousel .carousel-item .inner-content {
    position: absolute;
    margin: 2.5rem 0 0 2.5rem !important;
    width: 40% !important;
    top: 0;
}

.carousel-container .slickCarousel .carousel-item .inner-content h2 {
    font-size: 40px;
    font-weight: 400;
}

.carousel-container .slickCarousel .carousel-item .inner-content h2 a {
    color: #fff;
    font-size: 40px;
}

.carousel-container .slickCarousel .carousel-item .inner-content p {
    line-height: 1.5;
    font-size: 1rem !important;
    font-family: inherit !important;
    color: #fff !important;
    margin-bottom: 10px !important;
}

.divwrapper .treatment-accordion {
    padding: 0;
    margin-bottom: 10px;
}

.divwrapper .treatment-accordion h2 {
    color: #6dad46;
    font-weight: 300;
    width: 100%;
    padding: 15px 0;
    margin: 0;
}

.divwrapper .treatment-accordion h2 b {
    font-weight: 500;
}

.divwrapper .treatment-accordion h2 span {
    display: block;
    margin-bottom: 20px;
}

.divwrapper .treatment-accordion hr {
    display: block;
    border-color: #79818a;
    margin: 10px 0;
}

.divwrapper .treatment-accordion .promo-text {
    color: #5c6770;
    margin-bottom: 0;
}

.divwrapper .treatment-accordion .heading-figure {
    font-family: "Helvetica Neue", Helvetica, Arial, sans-serif !important;
    border: 0;
    font-size: 1.5rem;
    color: #6dad46;
    background: #f3f3f3;
    padding: 2rem 0 0 1rem;
}

.divwrapper .treatment-accordion .columncontrol .row {
    margin: 0;
}

.divwrapper .treatment-accordion.white .heading-figure,
.divwrapper .treatment-accordion.white .columncontrol .row {
    background: #ffffff;
}

.divwrapper .treatment-accordion .title + .title {
    margin-top: 10px;
}

.divwrapper .treatment-accordion .columncontrol .column-control-column p {
    font-size: 1.2rem;
    text-align: center;
    color: #ffffff;
}

.divwrapper .treatment-accordion .columncontrol .column-control-column {
    margin: 0 1rem;
}

.divwrapper .treatment-accordion.dark-blue .columncontrol .column-control-column {
    background: #005B7F;
}

.divwrapper .treatment-accordion.green .columncontrol .column-control-column {
    background: #6dad46;
}

footer .back-to-top a span {
    background: red;
}

.column-control-column div.image img {
    display: block;
    width: 100%;
    padding: 0;
}

.w-50 .col {
    width: 48%;
    margin: 1%;
}

.w-50 .col figure {
    margin: 0 !important;
}

.w-50 .col div.image img {
    display: block;
    padding: 0;
}

.video-mediatile {
    margin-bottom: 40px;
}

.video-mediatile + h2 {
    font-weight: 400 !important;
}

/* form overwrites */
.signin-register .form-control {
    line-height: 50px;
    height: 50px;
    border-radius: 0;
    border: 1px solid #ccc;
}

.signin-register label {
    margin: 0 0 5px;
    padding: 0;
    position: relative;
    left: -12px;
    font-weight: 400;
    color: #69B3E7;
    font-size: inherit;
}

.signin-register .checkbox {
    margin: 0 0 30px 20px;
    padding: 0;
}

.signin-register .checkbox label {
    font-size: inherit;
}

.signin-register .col {
    padding-right: 50px;
    border-right: 1px solid black;
}

.signin-register .col:nth-child(2) {
    padding-right: 0;
    border-right: none;
    padding-left: 50px;
}

.signin-register .btn.btn-default.text-uppercase.signin-submit.btn-contrast {
    line-height: 15px;
    height: 54px;
    padding: 0.9375rem 2.5rem;
    display: block !important;
    margin: 0 auto;
}

.header.intro h1 {
    width: inherit;
    font-size: 3rem !important;
}

.header.intro .cardcontainer:first-child, .main .header.intro .cardcontainer:first-child > .cardContainer {
    min-height: inherit;
}

.header.intro .cardContainer .cardContainer-content {
    text-align: center;
    padding-bottom: 2rem;
}

.header-video h2 {
    margin: 90px 0 -20px !important;
    display: block;
}

.jwplayer .jwdisplayIcon {
    border-radius: 50%;
    display: inline-block;
    margin-right: 20px;
    background: #2573BA !important;
    width: 105px !important;
    height: 105px !important;
}

#injection-video-8d14cf9d_display_button {
    background-image: none !important;
}

.jwplayer .jwdisplayIcon div {
    width: 0 !important;
    height: 0 !important;
    border-top: 20px solid transparent;
    border-bottom: 20px solid transparent;
    border-left: 25px solid #fff;
    display: inline-block !important;
    position: relative;
    margin-top: 47% !important;
    margin-left: 40%;
    border-radius: 1px;
    background-image: none !important;
}

/*Conferences and events setup*/
/*.events-container { margin-bottom: 40px;}*/
.events-container .col-md-3 {
    flex: 0 1 100%;
}

.events-container h3 {
    font-size: 1.25rem !important;
    display: block;
    padding-bottom: 50px;
    line-height: 1;
    overflow: auto;
    color: #333 !important;
}

.events-container h4 {
    color: #333;
    font-size: 1rem !important;
    display: block;
    padding: 0.5rem;
    line-height: 1;
    overflow: auto;
    display: inline-block;
    background: transparent;
}

.events-container p {
    color: #333 !important;
}

.events-container .accordion .accordionElementHeader h4 {
    margin: 0;
    padding: 0;
    font-weight: 200;
    line-height: 100%;
    text-transform: uppercase;
    float: left;
    color: #333;
    font-size: 1.25rem !important;
    font-family: inherit;
    width: auto !important;
    overflow: hidden;
    background: transparent !important;
}

.events-container .button.blue a {
    background: #2573BA !important;
    color: #fff !important;
    text-decoration: none !important;
    border: 0 !important;
}

.events-container .accordion .columncontrol .row {
    background: #fff;
    width: 100%;
    margin: 0 auto;
}

.events-container .cardContainer .cardContainer-content {
    min-height: 370px;
    position: relative;
}

.events-container .cardContainer-content .divwrapper.section {
    position: absolute;
    bottom: 30px;
    left: 0;
    right: 0;
}

.events-container .accordion {
    margin-top: 10px;
    border: 0;
    width: 100%;
    margin-bottom: 0;
    background: transparent;
}

.events-container .cardcontainer:first-child, .main .events-container .cardcontainer:first-child > .cardContainer {
    padding: unset;
    margin-bottom: 5px;
}

.events-accordion .accordion .accordionElementHeader h4 {
    font-size: 20px !important;
}

.events-container .cardContainer h4 {
    color: #333;
    font-size: 1rem !important;
    padding: 0.5rem;
    line-height: 1;
    overflow: auto;
    display: inline-block;
    background: transparent;
}

.events-container .cardContainer:hover .button a.netherLandsDefaultButton {
    background: #D1D3D3 !important;
}

.events-container .cardContainer:hover .button.d-blue a.netherLandsDefaultButton {
    background: #2573BA !important;
}

.events-container .button.blue a {
    background: #D1D3D3 !important;
    color: #333 !important;
    text-decoration: none !important;
    border: 0 !important;
}

.events-container .button.d-blue a {
    background: #2573BA !important;
    color: #fff !important;
    text-decoration: none !important;
    border: 0 !important;
}

.events-container .row {
    display: flex;
    flex-flow: row wrap;
    max-width: 100%;
    width: 100%;
}

@media all and (min-width: 376px) {
    .events-container .row {
        flex-flow: row wrap;
        width: 100%;
    }
}

@media all and (min-width: 768px) {
    .events-container .row {
        flex-flow: row wrap;
        width: 100%;
    }

    .events-container .col-md-3 {
        flex: 0 1 48.5%;
        margin: 0.75%;
    }
}

@media all and (min-width: 1024px) {
    .events-container .row {
        flex-flow: row wrap;
        max-width: none;
        width: 100%;
    }

    .events-container .col-md-3 {
        flex: 0 1 31.33%;
        margin: 0 2% 0% 0;
    }
}


/*Treatments setup*/
.treatments-container {
}

.treatments-container .col-md-3 {
    flex: 0 1 100%;
}

.treatments-container h3 {
    font-size: 1.25rem !important;
    display: block;
    padding-bottom: 50px;
    line-height: 1;
    overflow: auto;
    color: #333 !important;
}

.treatments-container h4 {
    color: #fff;
    font-size: 1rem !important;
    padding: 0.5rem;
    line-height: 1;
    overflow: auto;
    display: inline-block;
    background: transparent;
}

.treatments-container p {
    margin: 0 !important;
}

.treatments-container .accordion .accordionElementHeader h4 {
    margin: 0;
    padding: 0;
    font-weight: 200;
    line-height: 100%;
    text-transform: uppercase;
    float: left;
    color: #333;
    font-size: 1.25rem !important;
    font-family: inherit;
    width: 290px !important;
    overflow: hidden;
    background: transparent !important;
}

.treatments-container .accordion .accordionElementBody {
    padding: 20px 20px 25px 5px;
}

.treatments-container .button.blue a {
    background: #2573BA !important;
    color: #fff;
    border: 0 !important;
}

.treatments-container .accordion .columncontrol .row {
    background: #fff;
    width: 100%;
    margin: 0 auto;
}

.treatments-container .cardContainer .cardContainer-content {
    min-height: auto;
    position: relative;
}

.treatments-container .cardContainer-content p {
    color: #fff !important;
    font-size: 1.2rem;
}

.treatments-container .cardContainer-content .divwrapper.section {
    position: absolute;
    bottom: 30px;
    left: 0;
    right: 0;
}

.treatments-container .accordion {
    margin-top: 10px;
    border: 0;
    width: 100%;
    margin-bottom: 20px;
    background: transparent;
}

.treatments-container .cardcontainer:first-child, .main .events-container .cardcontainer:first-child > .cardContainer {
    padding: unset;
    margin-bottom: 5px;
}

.treatments-container .row {
    display: flex;
    flex-flow: row wrap;
    max-width: 100%;
    width: 100%;
}

.treatments-container .row .col:nth-child(2) {
    padding: 10px 0 25px 10px;
}

@media all and (min-width: 376px) {
    .treatments-container .row {
        flex-flow: row wrap;
        width: 100%;
    }
}

@media all and (min-width: 768px) {
    .treatments-container .accordion {
        margin-top: 10px;
        border: 0;
        width: 100%;
        margin-bottom: 80px;
        background: transparent;
    }

    .treatments-container .row {
        flex-flow: row wrap;
        width: 100%;
    }

    .treatments-container .col-md-3 {
        flex: 0 1 48.5%;
        margin: 0.75%;
    }

    .treatments-container .row .col:nth-child(2) {
        width: 49%;
        padding: 10px 0 25px 50px;
    }

    .treatments-container .cardContainer-content p {
        color: #fff !important;
        font-size: 1.5rem;
    }
}

@media all and (min-width: 1024px) {
    .treatments-container .row {
        flex-flow: row wrap;
        max-width: none;
        width: 100%;
    }

    .treatments-container .accordion .accordionElementBody {
        padding: 20px 50px 25px 5px;
    }

    .treatments-container .col-md-3 {
        flex: 0 1 32.3%;
        margin: 0.5%;
    }
}


.textblocks {
    padding: 0 20px 0 0;
}

.textblocks .row {
    position: relative;
    left: -20px;
    width: calc(100% + 20px);
}

.textblocks .col {
    margin-left: 1.25rem;
}

.textblocks .col-sm-6.col-md-6 {
    width: 100%;
}

.textblocks .col-sm-4.col-md-4 {
    width: 100%;
}

.textblocks .col-sm-6.col-md-3 {
    width: 100%;
}


@media all and (min-width: 516px) {
    .textblocks {
        padding: 0;
    }

    .textblocks .col-sm-6.col-md-6 {
        width: calc(50% - 1.25rem);
    }

    .textblocks .col-sm-4.col-md-4 {
        width: calc(50% - 1.25rem);
    }

    .textblocks .col-sm-6.col-md-3 {
        width: calc(50% - 1.25rem);
    }
}

@media all and (min-width: 768px) {
    .textblocks .col-sm-6.col-md-6 {
        width: calc(50% - 1.25rem);
    }

    .textblocks .col-sm-4.col-md-4 {
        width: calc(50% - 1.25rem);
    }

    .textblocks .col-sm-6.col-md-3 {
        width: calc(50% - 1.25rem);
    }
}

@media all and (min-width: 1024px) {
    .textblocks .col-sm-6.col-md-6 {
        width: calc(50% - 1.25rem);
    }

    .textblocks .col-sm-4.col-md-4 {
        width: calc(33.333% - 1.25rem);
    }

    .textblocks .col-sm-6.col-md-3 {
        width: calc(25% - 1.25rem);
    }
}


/* mobile menu setup */
.row-offcanvas-left.active {
    left: 0;
}

.row-offcanvas-left.active .mobile-menu-toggle.visible-xs- {
    background: #fff;
    left: 75%;
    padding: 0;
    width: 80px;
    height: 40px;
}

.row-offcanvas-left.active .sidebar-offcanvas {
    left: 0;
    position: absolute;
    z-index: 5000;
}

.mobile-menu-toggle {
    position: absolute;
    left: 20px;
    top: 10px;
}

@media all and (min-width: 516px) {
    .row-offcanvas-left.active .mobile-menu-toggle.visible-xs- {
        background: #fff;
        left: 58%;
        padding: 0;
        width: 80px;
        height: 40px;
    }
}

.shadow-below {
    background-color: #fff;
    position: relative;
    padding-bottom: 0;
    margin: 0;
    min-height: unset;
}

.shadow-below::after {
    display: none;
}

.shadow-below.empty {
    margin: 0;
}

.content .main.generic-page.full-width a {
    color: #2573BA;
    text-decoration: underline;
}

body .content .column-control-column .accordion h2 {
    margin: 0 0 30px 15px;
}

body .content .column-control-column .accordion p {
    margin: 0 0 0 15px !important;
}

/* search result */
#search_result li {
    padding-left: 5px;
    margin-bottom: 30px;
}

#search_result li strong {
    background: #f2f2f2;
}

.search-results-form .form-group {
    margin: 20px 0;
    padding: 0 90px 0 0;
    position: relative;
    max-width: 492px !important;
}

.search-results-form .form-control {
    height: 2.5rem;
    line-height: 2.5rem;
    background: #f2f2f2;
    border-radius: 0;
    border: none;
}

.search-results-form button {
    position: absolute;
    right: 0;
    top: 0;
    width: 85px;
    text-transform: uppercase;
    background: #6DAD46;
    height: 2.5rem;
    border-radius: 0;
}

.microsite-search-area {
    padding: 0 20px;
}

.content .microsite-search-area a {
    color: #2573BA;
}

.hcp-entrance .spots.blue .columncontrol .row > div {
    background: #2573BA !important;
    padding-bottom: 5rem;
    min-height: auto;
}

.hcp-entrance .columncontrol .row,
.hcp-entrance-normal .columncontrol .row {
    background: transparent;
    width: auto;
    margin: 0 auto;
    margin-bottom: 0;
}

.bannerPrivacyAcceptance {
    padding: 20px 160px;
    position: absolute;
    z-index: 50000;
}

.bannerPrivacyAcceptance {
    background: rgba(255, 255, 255, 0.95);
    color: #333;
    font-size: 14px;
    width: 100%;
    position: fixed !important;
    left: 0;
    top: 0;
    padding: 30px 15%;
}

.bannerPrivacyAcceptance button {
    width: 200px;
    display: block;
    padding: 10px 10px 30px;
    line-height: 1;
    font-size: 1rem;
}

.no-gradient .media img {
    object-fit: contain;
    height: auto !important;
}

.no-gradient .media > .media-body {
    background: none;
}
.disclaimer p{
    font-weight: normal;
}